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A regular glass of red wine 'can help women ward off breast cancer'



Women who enjoy a regular glass of red wine could reduce their risk of breast cancer, according to a new medical study.
The study, from Cedars-Sinai Medical Center in Los Angeles challenges the widely-held belief that all types of alcohol consumption heighten the risk of developing breast cancer.
Doctors have long known that alcohol increases the body's oestrogen levels, fostering the growth of cancer cells.

But the Cedars-Sinai study found that chemicals in the skins and seeds of red grapes slightly lowered oestrogen levels while elevating testosterone among pre-menopausal women who drank eight ounces of red wine nightly for about a month.
Researchers called their findings encouraging, saying women who occasionally drink alcohol might want to reassess their choices.

'If you were to have a glass of wine with dinner, you may want to consider a glass of red,' said study co-author Dr Chrisandra Shufelt.
'Switching may shift your risk.'


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Dr Shufelt noted that breast cancer is the leading type of women's cancer in the U.S., accounting for more than 230,000 new cases last year, or 30 percent of all female cancer diagnoses. An estimated 39,000 women died from the disease in 2011, according to the American Cancer Society.

In the Cedars-Sinai study, 36 women were randomised to drink either Cabernet Sauvignon or Chardonnay daily for almost a month, then switched to the other type of wine.

Blood was collected twice each month to measure hormone levels. Researchers sought to determine whether red wine mimics the effects of aromatase inhibitors, which play a key role in managing estrogen levels.

Aromatase inhibitors are currently used to treat breast cancer.

Investigators said the change in hormone patterns suggested that red wine may stem the growth of cancer cells, as has been shown in test tube studies.
Co-author Dr Glenn Braunstein said the results do not mean that white wine increases the risk of breast cancer but that grapes used in those varieties may lack the same protective elements found in reds.
'There are chemicals in red grape skin and red grape seeds that are not found in white grapes that may decrease breast cancer risk,' he said.
The study was published online in the Journal of



Women's Health.


طيب جاء الزميل الامبراطور بمقال يقول أن شرب كوب من الخمور الحمراء ( الإيثانول ) يوميا يقى من سرطان الثدى

طيب اتفضل
http://foodforbreastcancer.com/artic...sk-drink-it%3F

Red wine: Should breast cancer patients and those at high risk drink it?

Red wine has been shown to help prevent and inhibit the development of breast cancer in mice. Red wine can inhibit aromatase, the production of estrogen from androgens within the body. It has also been shown to limit the toxic skin effects of radiation therapy for breast cancer. However, alcohol consumption has also been found to be associated with increased risk of breast cancer in the general population. Do the potential benefits of drinking red wine outweigh its harmful effects?


Effects of alcohol on breast cancer risk and recurrence

Like grapes, red wine is an excellent source of resveratrol and other polyphenols that have been shown to counteract the development of breast cancer. Resveratrol has the ability to suppress proliferation of breast cancer cells and promote cell death, as well as inhibiting aromatase, which is important for reducing growth-stimulatory effects in estrogen-dependent breast cancer. Resveratrol has also been shown to enhance the effectiveness of radiation treatment.

Alcohol consumption is positively correlated with breast cancer risk, particularly hormone receptor positive (ER+/PR+) and lobular breast cancer. The association between alcohol intake and increased breast cancer risk is strongest in postmenopausal women.

Alcohol has also been shown to increase risk of recurrence in breast cancer survivors. A major prospective study which included 1,897 breast cancer patients from Kaiser Permanente Northern California reported that moderate alcohol consumption was associated with increased breast cancer recurrence. The majority of the women (89%) drank wine. Compared with abstinence from alcohol, drinking at least 6 g/day of alcohol was found to be associated with 1.35 times the risk of breast cancer recurrence. The risk of recurrence was higher among postmenopausal and overweight women. The authors concluded that consuming three to four alcoholic drinks or more per week after a breast cancer diagnosis may increase risk of breast cancer recurrence.

On the other hand, there is some limited evidence that drinking wine may protect BRCA1 mutation carriers against breast cancer.

How much red wine is safe for breast cancer survivors?

Drinking red wine is on balance harmful for breast cancer patients and those at relatively high risk for breast cancer. The potential benefits of resveratrol and other chemopreventative substances appear to be overwhelmed in the body by the cancer-promoting effects of the alcohol in red wine. Red grapes, blueberries, blackberries and cranberries are good alternate sources of resveratrol. Also, some alcohol-free red wines are available that might be a good substitute for some.

Other spices and foods such as turmeric, parsley, ginger, holy basil, garlic, onions, and mangoes have also been found to protect against radiation damage. In particular, the curcumin in turmeric has been found in mouse models to effectively protect skin from radiation damage, while at the same time sensitizing breast cancer cells to radiation and making them more susceptible to its effects.

For breast cancer patients, those in remission and those at high risk for breast cancer, the cancer promoting properties of red wine outweigh its potential benefits (including preventing cardiovascular disease). Drinking purple grape juice and using red wine in cooking is preferable to drinking red wine. However, based on the evidence to date, a glass of red wine with food everyother day might be a safe level of consumption

و ملخص المقال السابق هو أن :

1-الخمور تزيد من خطر الإصابة بسرطان الثدى و بالأخص عودته مرة أخرى بعد علاجه

2- هناك أدلة ضعيفة على أن الخمور الحمراء قد تقى من سرطان الثدى و لاحظوا كلمة ضعيفة

3- بالنسبة لمن أصيبوا بسرطان الثدى من قبل أو النساء المعرضات له بدرجة عالية فإن أضرار الخمور أكثر من أثرها الواقى

4- الأثر الواقى للخمور الحمراء بسبب وجود بعض المواد بها مثل الريسفراترول
و تلك المواد لها مصادر أخرى مثل العنب الأحمر و بعض الفواكه الأخرى

5- شرب كوب من الخمر كل 48 ساعة قد يكون آمن لكن أكثر مما سبق له أثره الضار