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Escitalopram
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Escitalopram

Systematic (IUPAC) name
(S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
Identifiers
CAS number 128196-01-0
ATC code N06AB10
PubChem 146570
DrugBank APRD00683
ChemSpider 129277
Chemical data
Formula C20H21FN2O
Mol. mass 324.392 g/mol
(414.43 as oxalate)
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 80%
Protein binding ~56%
Metabolism Liver, specifically the enzymes CYP3A4 and CYP2C19
Half life 27–32 hours
Excretion ?
Therapeutic considerations
Pregnancy cat. C

Legal status Rx Only (U.S.)

Routes Oral
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Lexapro tablets
Cipralex brand escitalopram package and tablet sheetEscitalopram (trade names Lexapro, Cipralex) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment in adults with major depressive disorder, generalized anxiety disorder, social anxiety disorder, or panic disorder. Escitalopram is the S-stereoisomer (enantiomer) of the earlier Lundbeck drug citalopram, hence the name escitalopram. Escitalopram is noted for its high selectivity of serotonin reuptake inhibition and has side effects typical for the SSRI class.

http://en.wikipedia.org/wiki/Escitalopram

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http://www.medicinenet.com/escitalopram/article.htm


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